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Allylestrenol

Allylestrenol

Product Details

Name:Allylestrenol

Synonyms:13-Methyl-17-prop-2-enyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol

MF:C21H32O

MW:300.48

CAS RNumber:432-60-0

EINECS:207-082-9


Brief Introduction

Allylestrenol (BAN/INN), also known as allyloestrenol and allyl estrenol, is a synthetic progestogen used to prevent threatened miscarriage, recurrent pregnancy loss and premature labor. In men, it has also been studied as a treatment for benign prostatic hyperplasia, with encouraging results.

 

Allylestrenol is sold under several trade names, including Gestin, Turinal,Gestrenol, Gestanin, Gestanol or Gestanon, Maintaine, Orageston, and Profar. It is currently not marketed in the United States, United Kingdom, or Canada, but as of 2011, is extensively used in Bangladesh,Japan, Russia, India, and much of Southeast Asia.


TEST ITEMS

               SPECIFICATION

RESULTS

Description

 White or Almost White Crystalline Powder

white powder

Identification

 A.B.

Positive

Assay

97.0~103.0%

99.3%

Specific Rotation

+101°~+105°

+102.6°

Loss On Drying

1.0%max

0.27%

Melting Point

153~157°C

153.0~155.0°C

Organic Volatile Impurities

meets the requirement.

Conforms

Related Substances

meets the requirement.

Conforms

Residual Solvents

meets the requirement.

Conforms

Particle Size

100% ≤ 20 microns

Conforms

Conclusion

The specification conform with USP30 standard


Application

Allylestrenol was used to treat 375 women with threatened pregnancies. Results show that this drug is capable of maintaining pregnancy in a large series of ambulant patients and is safe for both mother and child. Allylestrenol does not maintain pregnancy if placental dysfunction is present, however. Newborns whose mothers are treated with allylestrenol have slightly higher birth weights than controls. The possible role of allylestrenol in this process is discussed. At high doses, allylestrenol effectively stops premature labor, suggesting a selective action on the myometrium.


Packaging & Shipping

Package: 25kgs/drum, plastic-bag inside, aluminum foil bag or fiber drum outside.

Our Services
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Fastest delivery: Sample order in stock and 3-7 days for mass production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you can also choose your own shipping forwarder.


Contact us

Address: Room 810, Unit 1, Zhuque Seven-Star International Apartment, Zhuque Street,Yanta District, Xi'an, 710075

Tel: 0086-029-68750642/68750658

Fax: 0086-029-68750658

Email: info@nutragreenlife.com

Web: www.nutragreenlife.com


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