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Betamethasone

Betamethasone

Product Details

Name:Betamethasone

CAS Number:378-44-9

Formula:C22H29FO5

Molecular Weight:434.50

Synonyms:

Celestene;Prestwick_703;9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;Rinderon A;Cidoten;beta-Methasone alcohol;Betamethazone;Bedifos;Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17, 21-trihydroxy-16-methyl-, (11.beta.,16.beta.)-;9.alpha.-Fluoro-16.beta.-methylprednisolone;Desacort-beta;Betsolan;Sch 4831;.beta.-Methasone alcohol;Pregna-1,4-diene-3,20-dione,9-fluoro-11,17,- 21-trihydroxy-16-methyl-,(11a,16a)-;Becort;Betacortril;Prednisolone, 9-fluoro-16beta-methyl-;Betamamallet;Betamethasone (JP14/USP);9-alpha-Fluoro-16-beta-methylprednisolone;Betafluorene;9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;Betapredol;Visubeta;

EINECS:206-825-4

Density:1.32 g/cm3

Melting Point:235-237 °C

Boiling Point:568.2 °C at 760 mmHg

Flash Point:297.5 °C

Appearance:white to off-white solid

ITEMS

SPECIFICATIONS

RESULTS

Appearance

White to almost white,odorless, crystalline powder

 Conforms

Identification

Complies with the stanard  

Conforms

Loss on drying

≤0.5%

0.08 %

Residue on Ignition

≤0.3%

0.3%

Specific on rotation

+118~ +126.

+ 123.4 °

Melting point

50 ℃ ~ 60 ℃

50 ℃ ~ 60 ℃

Sulphate ash

≤0.1%

0.05%

Heavy metals

≤ 20 ppm

< 20ppm

Related substance

Total impurity ≤2.0%  

Single impurity ≤.20%

0.41%

0.12%

Methanol

≤ 3000 ppm

Conforms

Ethylacetate

≤ 3000 ppm

Conforms

DMF

≤ 3000 ppm

Conforms

Acetone

≤ 3000 ppm

Conforms

Dichlormethane

≤ 3000 ppm

Conforms

Assay

97.0~103.0%

100.0 %

Conclusiion

This product complied with the standard of EP 6.0


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