Name:Betamethasone
CAS Number:378-44-9
Formula:C22H29FO5
Molecular Weight:434.50
Synonyms:
Celestene;Prestwick_703;9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;Rinderon A;Cidoten;beta-Methasone alcohol;Betamethazone;Bedifos;Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17, 21-trihydroxy-16-methyl-, (11.beta.,16.beta.)-;9.alpha.-Fluoro-16.beta.-methylprednisolone;Desacort-beta;Betsolan;Sch 4831;.beta.-Methasone alcohol;Pregna-1,4-diene-3,20-dione,9-fluoro-11,17,- 21-trihydroxy-16-methyl-,(11a,16a)-;Becort;Betacortril;Prednisolone, 9-fluoro-16beta-methyl-;Betamamallet;Betamethasone (JP14/USP);9-alpha-Fluoro-16-beta-methylprednisolone;Betafluorene;9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;Betapredol;Visubeta;
EINECS:206-825-4
Density:1.32 g/cm3
Melting Point:235-237 °C
Boiling Point:568.2 °C at 760 mmHg
Flash Point:297.5 °C
Appearance:white to off-white solid
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | White to almost white,odorless, crystalline powder | Conforms |
Identification | Complies with the stanard | Conforms |
Loss on drying | ≤0.5% | 0.08 % |
Residue on Ignition | ≤0.3% | 0.3% |
Specific on rotation | +118~ +126. | + 123.4 ° |
Melting point | 50 ℃ ~ 60 ℃ | 50 ℃ ~ 60 ℃ |
Sulphate ash | ≤0.1% | 0.05% |
Heavy metals | ≤ 20 ppm | < 20ppm |
Related substance | Total impurity ≤2.0% Single impurity ≤.20% | 0.41% 0.12% |
Methanol | ≤ 3000 ppm | Conforms |
Ethylacetate | ≤ 3000 ppm | Conforms |
DMF | ≤ 3000 ppm | Conforms |
Acetone | ≤ 3000 ppm | Conforms |
Dichlormethane | ≤ 3000 ppm | Conforms |
Assay | 97.0~103.0% | 100.0 % |
Conclusiion | This product complied with the standard of EP 6.0 | |