Banner
Home > Products >> Nutraceuticals

Donepeziz Hydrochloride

Donepeziz Hydrochloride

Product Details

SPECIFICATION

Product nameDonepeziz hydrochloride

Appearance

White Powder
OdorCharacteristic

Assay

≥98%

Loss on drying

≤1.0%

Ash

≤1.0%

Heavy Metal

<10ppm

As         

<2ppm
Lead(Pb)<2ppm
Solvent UsedEthanol & Water
Total Plate Count<1000cfu/g
Yeast & Moulds<100cfu/g  

E.Coli.

Negative

Salmonella

Negative

Conclusion  

Conform with specification

Packing

25 kg/paper drum
Storage

Store in sealed containers at cool & dry place.

Protect from light, moisture and pest infestation.


Shelf life                                                

2 years when properly stored


USAGE

Product nameDonepeziz hydrochloride
UsageDonepezil is a long-acting Blzheimer disease (AD) of the symptomatic treatment drugs. AD is a loss of memory as the main performance, accompanied by other cognitive impairment of acquired intelligence impairment. Nearly 30 years of research indicate that:AD cholinergic neuron degeneration was the cause of memory loss, disorientation, behavioral and personality changes, this cholinergic theory has been research confirmed histologically. Donepezil hydrochloride is the second generation of cholinesterase (ChE) inhibitor, its therapeutic effect is reversible inhibition of acetylcholinesterase (AchE) caused by the hydrolysis of acetyl cholyl increased content of acetylcholine receptor site. Donepezil may also have other mechanisms, including direct effect on peptide disposal, neurotransmitter receptors or Ca2+ channel.
                 
           Donepezil hydrochloride selective affinity for AchE than butyrylcholinesterase (BchE) 1250 times stronger, it could obviously inhibit the brain tissues of ChE, but for the heart (cardiac) or small (Ping Huaji) had no effect on breast tissue, may have the effect of (striated); central nervous toxicity than tacrine small.


Feedback