Banner
Home > Products >> API And Intermediate >> Steroids

Estradiol

Estradiol

Product Details

Product name:Estradiol  

CAS:50-28-2

Assay:>99%

Appearance:White Cyrstalline Powder

MF:C18H24O2

MW:272.38

EINECS:200-023-8

Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.Estradiol is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Other uses include prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. Estradiol is sometimes used as part of cancer treatment in women and men.Estradiol may also be used for other purposes not listed in this medication guide

Product Name

Estradiol

CAS No.

50-28-2

Quantity

100kg

Reference Standard

USP36

SUBJECTS

SPECIFICATION

RESULTS

Appearance

White or almost white crystalline powder

White crystalline powder

Optical rotation

+76°~+83°

+77.58°

Melting point

173~179°C

174.5~177.5°C

Identification

IR 
UV

Conform 
Conform

Impurities

Single impurity≤0.5%
Total impurities≤1.0%

<0.5%
<1.0%

Water

≤3.5%

3.05%

Assay

97.0%~103.0%

98.62%

Conclusion

The products meet the specification of USP36.

Estradiol, or more precisely, 17β-estradiol, is a steroid and estrogen sex hormone, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο (oistros, literally meaning "verve or inspiration")and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol is produced especially within the follicles of the female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone).One principle pathway then converts progesterone to its 17-hydroxy derivative, 17-hydroxyprogesterone, and then to Δ4-androstenedione via sequential cytochrome P450-catalyzed oxidations.[citation needed] Action of aromatase on Δ4-androstenedione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.[citation needed] Alternatively, Δ4-androstenedione can be converted into the androgen, testosterone, which in turn can be converted directly into 17β-estradiol.


Packaging & Shipping

Package: 25kgs/drum, plastic-bag inside, aluminum foil bag or fiber drum outside.

Our Services
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Fastest delivery: Sample order in stock and 3-7 days for mass production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you can also choose your own shipping forwarder.


Contact us

Address: Room 810, Unit 1, Zhuque Seven-Star International Apartment, Zhuque Street,Yanta District, Xi'an, 710075

Tel: 0086-029-68750642/68750658

Fax: 0086-029-68750658

Email: info@nutragreenlife.com

Web: www.nutragreenlife.com



Hot Tags: estradiol estradiol powder estradiol USP estradiol manufacture bulk estradiol pharmaceutical raw material high quality estradiol

Feedback