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Ethinyl Estradiol

Ethinyl Estradiol

Product Details

Name: Ethinyl Estradiol

Spec.: 99% HPLC

Appearance: White powder

Other name: Ethinylestradiol;EE;Estinyl  

EINECS No.: 200-342-2

CAS: 57-63-6

M.F.: C20H24O2

M.W.: 296.4



Ethinyl estradiolalso sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl œstradiol, is a derivative of 17β-estradiol(E2), the major endogenousestrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.

Transdermal ethinyl estradiol carries a greater risk of clot formation and venous thromboembolism than 17 beta estradiol, which some have theorized to be related to different amounts of hepatic metabolism after absorption. The same contraindications and precautions apply for EE as with other estrogen medications.

Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.

EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.

The major concern with unopposed estrogen is of endometrial cancer. The medication is generally prescribed withprogesterone in the setting of birth control.

ItemStandardTest Results

Identification

A.H-NMR:Comply with the structure

Complies

B.LC-MS:Comply with the structure

Complies

C.The IR spectrum of sample should be identical with that of reference standard;

Complies

D.HPLC-ESI-MS

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Complies

Crystallinity

meets the requirements.

Complies

Loss on drying

≤2.0%

0.19%

Heavy metals

≤10 ppm

<10ppm

Water

≤1.0%

0.1%

Sulphated ash

≤0.5%, determined on 1.0 g.

0.009%

Related substances

Unspecified impurities: for each impurity

≤0.10%

<0.10%

Total Impurity

≤0.5%

0.18%

Purity

≥99.0%

99.7%

Assay

99.0%~101.0%

99.8%

Microbiological Analysis

Total plate count

≤1000cfu/g

Complies

Yeast and Moulds

≤100cfu/g

Complies

E. Coli.

Absent

Negative

Salmonella

Absent

Negative

S.aureus

Absent

Negative

Storage

Preserve in well-closed, light-resistant and airtight containers.

Complies

 

Application

1 Applied in pharmaceutical field, Ethinyl Estradiol is used as medicine toTreat female hypogonadism;

2 Ethinyl Estradiol also can be used to treat estrogen of endometrial cancer.

Main Function

1 Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills (the Pill)2 Ethinyl Estradiol was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism;

3 Ethinyl Estradiolis released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication;

4 Ethinyl Estradiol can be used for the management of menopausal symptoms and female hypogonadism;

5 Ethinyl Estradiol is generally prescribed with progesterone in the setting of birth control.

Packaging & Shipping

Package: 25kgs/drum, plastic-bag inside, aluminum foil bag or fiber drum outside.

Our Services
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Fastest delivery: Sample order in stock and 3-7 days for mass production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you can also choose your own shipping forwarder.


Contact us

Address: Room 810, Unit 1, Zhuque Seven-Star International Apartment, Zhuque Street,Yanta District, Xi'an, 710075

Tel: 0086-029-68750642/68750658

Fax: 0086-029-68750658

Email: info@nutragreenlife.com

Web: www.nutragreenlife.com


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