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Mometasone Furoate

Mometasone Furoate

Product Details

CAS 83919-23-7

Chemical Name:Mometasone furoate, 9-Chloro-17-(2-chloroacetyl)-11, 17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate

Molecular Formula:C27H30Cl2O6

Molecular Weight:521.44


Item

Specifications

Results

Description  

White or almost white  crystalline powder 

white crystalline powder

Identification  

complies with the standard  

complies

Specific rotation  

+56.0°~+62.0°   

+59.2°

Loss on drying  

max.0.5%   

0.05%

Residue on ignition                    

max.0.1%  

0.05%

Heavy metals                      

max.30ppm    

complies

Related substance  (TLC)  

-single impurity                        

max. 1.0%

complies

- total impurities                       

max. 2.0%

complies

Assay

(HPLC, based on drying)

97.0%~102.0%   

98.3%

Conclusion

The results conforms with USP32 standards


Application:Local use of corticosteroids in effect, anti-inflammatory, relieving itching and vascular contraction effect. For Skin disease patients, can alleviate inflammation and itching, especially with the reaction of the patients have cortisone.


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