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Prednisone

Prednisone

Product Details

Product Name:Prednisone

Synonyms:1,2-Dehydrocortisone;1,4-pregnadiene-16-alpha,21-diol-3,11,20-trione;11,20-trione,17,21-dihydroxy-pregna-4-diene-3;11,20-trione,17,21-hydroxy-pregna-4-diene-3;Ancortone;Bicortone;Colisone;Cortan

CAS:53-03-2

MF:C21H27FO6

MW:394.44


Product Introduction

Prednisone Chart prednisone prednisone has anti-inflammatory and anti-allergic effects, can inhibit the proliferation of connective tissue and reduce the permeability of the capillary wall and cell membrane, reduce the inflammatory exudate, and inhibit histamine and other toxic substances the formation and release. This product can promote protein degradation into sugar, reduce glucose utilization. Thus the blood sugar and liver glycogen are increased, there may be diabetes, and increased gastric secretion, increase appetite. When severe toxic infection when used in conjunction with a number of antibiotics, may have good cooling, anti-drug, anti-inflammatory, anti-shock symptoms and promote action. Its sodium retention and potassium effects than cortisone row of small, strong anti-inflammatory and anti-allergic effects, fewer side effects, it is more commonly used.

Specification

TESTS

SPECIFICATIONS

RESULTS

Description

A white or almost white crystalline powder

A white crystalline powder

Specific rotation

Between +183°~+190°

+187.19°

Absorptivity

373~397

382.46

Identification

Reaction is red

Reaction is red

Become a turquoise

Become a turquoise

Retention time is consistent with the retention time of the reference solution

Conforms

IR absorption meets specification(Spectrum set 549 figure)

Conforms

Related substances

Prednisone≤0.5%

0.06%

Cortisone acetate≤1.5%

0.56%

Total impurities≤2.0%

0.76%

Loss on drying

≤0.5%

0.12%

Assay

97.0~102.0%

98.45%

Residual solvents

Ethanol≤5000ppm

1056ppm

Ethyl acetate≤5000ppm

ND

Packaging and storage

Store protected from light.

CONCLUSION

Conform to CP2010 monograph

Function    

 1)Helps protect the liver

 First, this bile acid acts to restore bile acid transporters. Doing this allows bile to flow normally via these transporters. Not only that, but it also acts to prevent formation of the toxic steroid glucuronides in the first place. A 2003 study showed that TUDCA is a noncompetitive inhibitor of steroid glucuronidation in vivo and in vitro. This means fewer toxic metabolites will be made in the first place! And, TUDCA may also increase the excretion of any glucuronide metabolites that do get formed, so they will not be around long enough in the liver to start down regulating any bile acid transporters.

 2)Aids in production of bile

 3)Lose weight

 Promotes healthy cholesterol levels

 Ursodeoxycholic acid (udca) is a secondary bile acid in the body. It also helps the digestive track breakdown cholesterol. It is the only FDA approved drug to treat cirrhosis. It has been shown to reduce jaundice and liver enzymes.

 4)Protects the eyes

 The natural form of the bile, most commonly found in bears, has been used in traditional Chinese medicine for thousands of years to treat a variety of ailments and conditions. There is even a 3,000-year-old scroll that mentions it as being a cure for blindness


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Tel: 0086-029-68750642/68750658

Fax: 0086-029-68750658

Email: info@nutragreenlife.com

Web: www.nutragreenlife.com


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