Tibolone

Product Details

English name: Tibolone

Chinese alias: a different acetylene nandrolone;17 - hydroxy - 7 alpha - methyl - 19 - to a pregnant steroid - 5 (10) - ene - 20 - acetylene - 3 - ketone;Methyl isopropyl norethindrone.Methyl isopropyl ketone of acetyleneEINECS: 227-069-1
CAS NO. : 5630-53-5
MF:C21H28O2

Description

1). Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile.It has also been investigated as a possible treatment for female sexual dysfunction.

2). Tibolone (Livial/Liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.

3). When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness.Tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.

 
SPECIFICATION

Applications

1). Tibolone is a synthetic hormone derived from the Mexican yam.

2). Tibolone is used to replace the body’s natural sex hormones. It is converted in the body into three other substances which act like the hormones oestrogen, progesterone or testosterone in different tissues.

3). Tibolone acts like oestrogen in the brain (preventing flushes), bone (preventing bone loss) and vaginal tissue (preventing dryness and soreness).

4). Tibolone also acts like progesterone in the womb to prevent overgrowth of the endometrium and subsequent bleeding. A woman who has not had a hysterectomy does not need to take a progesterone if she is taking tibolone.

5). Tibolone has testosterone-like activity that appears to play a role in enhancing women’s mood and libido, although response is variable.

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